Careers
Join a team delivering innovation in precision medicine
Vesigen is uncovering new therapeutic opportunities along a vast landscape made possible by ARMMs technology.
VP, Biology and Drug Discovery
Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, called ARMMs (ARRDC1 Mediated Microvesicles), can be used to precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.
Responsibilities
Qualifications
What we provide:
Vesigen Therapeutics is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.
Sci II/Senior Scientist, ARMMs Engineering
Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, called ARMMs (ARRDC1 Mediated Microvesicles), can be used to precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.
Vesigen is seeking a talented and highly motivated Scientist II/Sr Scientist to join our team and contribute to the development of the company’s exciting ARMMs technology across multiple disease areas. The ideal candidate will have an established background in molecular biology, vector design and optimization, membrane protein biology, and antibody engineering. This is an opportunity to innovate and impact preclinical drug discovery efforts in a dynamic biotech start-up environment.
Responsibilities:
Develop appropriate assays to evaluate new constructs and strategies to modify various ARMMs properties.
Qualifications:
What we provide:
Vesigen Inc., is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.
Scientist/Sr Scientist, Ocular Drug Discovery
Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, called ARMMs (ARRDC1 Mediated Microvesicles), can be used to precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.
Vesigen is seeking an analytical and highly motivated Scientist to join our Ocular and CNS Drug Discovery team to help drive ophthalmology-centric preclinical programs with the company’s ARMMs technology. The candidate will play a significant role in the entire spectrum of the drug discovery process including ideation, target identification & validation, and disease-related biomarkers.
Responsibilities
· Expand, strengthen, and fine-tune our current ocular biodistribution datasets in diverse in vivo models using multiple routes-of-administration and payloads/modalities. You will conduct routine subretinal/intravitreal surgeries in rodents on-site and manage CROs for specialized surgeries in large animal models.
· Conceptualize, design, and execute experiments independently.
· Maintain accurate experimental records and study reports. Ensure that discovery work and data collection are conducted with utmost attention to quality and ethical standards and, in compliance with regulatory and QC guidelines.
· Routinely implement histology, non-invasive diagnostics, electrophysiology, and behavior assays to assess ocular biodistribution, toxicological outcomes, and efficacy.
· Work closely with colleagues in biology, computational biology, and therapeutic discovery group for design and screening of ARMMs for ocular drug candidates. You will be part of a group effort and help select appropriate assays, and in vitro, ex vivo & in vivo screening criteria. You will participate in the screening campaigns and importantly, help generate high-confidence data that are substantiated by in vivo findings.
· Facilitate and maintain relationships with CROs, external academic groups, and scientific and key opinion leaders. Coordinate study design and execution, manage timelines, and data quality control. Analyze and present findings to various stakeholders.
· Present research findings to the Vesigen Leadership and various stakeholders
· Attend scientific and industry conferences to engage the broader scientific community.
Qualifications
· Ph.D. in Ophthalmology/Neuroscience/Neurobiology with relevant surgical experience or a Ph.D. with 2+ years of relevant experience in industry or academia.
· Deep expertise and understanding of degenerative pathophysiology, animal models, and an experience in using these animal models to assess therapeutic outcomes.
· Experience in conducting in vivo, ex vivo, and in vitro experiments – in ophthalmology using intravitreal and subretinal routes of administration.
· Ability to conduct in vivo studies using rodent model systems. An ideal candidate will demonstrate a deep understanding of comparative ocular anatomy, pathophysiology, proficiency and independence in the laboratory, experience in ocular drug delivery, small animal surgical skills in ophthalmology, and a proven ability to complete ocular drug discovery projects.
· Proficiency in histology (including sections and flatmount preparations of the retina and the RPE), immunohistochemistry, and cell culture is expected. Hands-on experience with confocal imaging, quantitative image analysis, and quantitative RNA in situ hybridization is highly desirable but not an absolute must.
· Demonstratable experience of working independently as well as a member of the team on scientific projects.
· Excellent communication and organizational skills.
· Ability to quickly learn and pivot as guided by data. Candidates with a strong background in CNS drug delivery and discovery, surgery, and an understanding of retinal anatomy & physiology are welcome to apply.
What we provide:
Vesigen Therapeutics is an equal-opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.
Scientist II/Sr Scientist, Immune Modulation
Scientist II/Sr Scientist, Immune Modulation
Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, called ARMMs (ARRDC1 Mediated Microvesicles), can be used to precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.
We are seeking a highly motivated and detail-oriented scientist to join our team and contribute to developing and optimizing the company’s exciting ARMMs platform toward a novel immunotherapy program. The ideal candidate will be an enthusiastic, innovative individual with a scientific background in immunology who will thrive in our fast-paced, entrepreneurial team environment.
Responsibilities:
Qualifications:
What we provide:
Vesigen Therapeutics is an equal-opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.
Don’t see anything that matches your experience? Contact us using the form.
At Vesigen, you’ll join a rapidly growing biotech company engineering the medicines of tomorrow. We are focused on developing therapies that transform patients’ lives.
We value scientific curiosity and collaboration from start to finish. If you share these attributes and you’re ready for the challenge of your career, we’d like to hear from you.