Careers

Join a team delivering innovation in precision medicine

With our pioneering advances in engineering ARMMs, we are poised to usher in a new era of precision medicine. Our innovative therapeutic approach presents exciting opportunities for those seeking to make a meaningful impact to transform the lives of patients. If you are searching for a career that combines cutting-edge science and the potential to revolutionize targeted therapeutics, then you have come to the right place.

Current opportunities

Open Positions

VP, Biology and Drug Discovery

Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, called ARMMs (ARRDC1 Mediated Microvesicles), can be used to precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.

Responsibilities

Work closely with executive management team to prioritize and advance preclinical drug development programs from concept through IND submission
Articulate vision, strategy and performance metrics for platform and drug discovery arms at Vesigen
Manage all ARMMs engineering and drug discovery functions to develop existing programs, establish go/no-go decision points, introduce new programs, and to identify new opportunities to expand scope of current programs
Lead scientific activities with strong attention to rigor and differentiation to permit advancing drug candidates as first-in-class/best-in-class therapies for diseases with unmet need
Track literature and identify opportunities to introduce new design strategies and/or applications for ARMMs
Implement and help inform intellectual property strategy, working closely with executive management and IP teams
Work with CROs, academic collaborators, and other biotech/pharma companies
Assist in projecting resources and financial budgets to support discovery programs from the exploratory stage through the development stage to clinical

Qualifications

PhD/MD with strong background in Molecular Biology, Cell Biology, Virology, Immunology, Pharmacology, or related field
10+ years of experience in drug discovery, platform development, or combination thereof in biotech or pharma
Proven track record leading teams in platform development and/or drug discovery settings – experience with viral and/or non-viral delivery and/or platform builds desirable
Demonstrated expertise and track record in drug discovery in a range of therapeutic areas, ideally from conceptualization through lead optimization and candidate selection
Track record of excellence and scientific expertise as demonstrated by peer-reviewed publications
High level of rigor and attention to detail, and ability to think out of the box and innovate
Strong leadership, communication skills, and ability to perform at a high level in a fast-paced environment

What we provide:

Competitive pay
High-quality and inclusive medical, dental, and vision coverage options
Deductible fully funded HSA for medical expenses and dependent care expenses
Paid Life, LTD, and STD insurance coverage
401k Program
ACI Employee Assistance Program
15 paid holidays, including a winter shutdown week
15 days PTO (accrued)
Unlimited Sick Time Off
Free parking or subsidized commuter passes

Vesigen Therapeutics is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

Sci II/Senior Scientist, ARMMs Engineering

Vesigen is seeking a talented and highly motivated Scientist II/Sr Scientist to join our team and contribute to the development of the company’s exciting ARMMs technology across multiple disease areas. The ideal candidate will have an established background in molecular biology, vector design and optimization, membrane protein biology, and antibody engineering. This is an opportunity to innovate and impact preclinical drug discovery efforts in a dynamic biotech start-up environment.

Responsibilities:

Expression construct design and optimization to evaluate engineering of ARMMs intraluminal payloads and targeting moieties (eg, antibodies, receptor ligands, etc…), including other vesicle surface-associated modifications.
Custom design of vectors to enable rapid swapping of elements for optimization of transgene expression or to alter other elements, such as linkers.
Execute and oversee testing of constructs by transient transfection using approaches such as PEI, lipoplex, or electroporation

Develop appropriate assays to evaluate new constructs and strategies to modify various ARMMs properties.

Contribute to design of assays to support platform and discovery activities, as they relate to vector design, including appropriate evaluation of transgene expression, payloading/surface modification of ARMMs, and determination of particle potency.
Analyze and present experimental progress and results in team meetings.
Collaborate across research function and with process development team to enable transfer of knowhow and scale-up of engineered ARMMs production.

Qualifications:

Ph.D. in molecular biology, protein biochemistry, virology or related life sciences field and 0-5 years of hands-on industry experience strongly preferred. B.S./M.S. with 10 or more years of relevant experience will also be considered for the role.
Excellent understanding of membrane protein structure and antibody engineering including scFv (single chain variable fragment) and nanobodies.
Previous experience in molecular mechanisms of virus-host interactions highly desirable
Extensive experience in molecular biology and with relevant online tools and software packages eg: SnapGene or similar software.
Experience with construct design, introduction into the model system/cell line, including transfection, transduction, and electroporation.
Strong background in cell-based assays and readouts by flow cytometry, qPCR, Western Blot, ELISA, and high-content imaging.
Experience in and/or commitment to training and mentoring junior team members
Ability to collaborate effectively within a fast-paced, multidisciplinary environment.
Excellent organizational skills and record keeping.
Good written and oral communication skills and the ability to multitask with an evolving workload.
Motivated, self-starter with enthusiasm to learn and contribute.

What we provide:

Competitive pay
High-quality and inclusive medical, dental, and vision coverage options
Deductible fully funded HSA for medical expenses and dependent care expenses
Paid Life, LTD, and STD insurance coverage
401k Program
ACI Employee Assistance Program
15 paid holidays, including a winter shutdown week
15 days PTO (accrued)
Unlimited Sick Time Off
Free parking or subsidized commuter passes

Vesigen Inc., is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

Accounts Payable Associate

Vesigen Therapeutics is a biotechnology company developing novel therapeutics enabled by engineering naturally existing vesicles for delivery. Vesigen’s patented technology, ARMMs (ARRDC1 Mediated Microvesicles), can precisely deliver a wide range of payloads, including gene editing complexes, proteins, and RNAs in vivo. Our team of seasoned drug hunters is committed to leveraging the novel ARMMs technology to develop transformative medicines and address unmet medical needs.

Vesigen is seeking a highly motivated and detailed oriented account payable professional to join our team and contribute to establishing the accounting department with the Director of Finance. This is an exciting opportunity to join a growing company and hone skills in providing financial, administrative, and clerical support to the organization. The ideal candidate will be a driven individual looking to work in a fast-paced, dynamic biotech start-up environment.

Responsibilities

Creating journal entries and financial reports
Entering and paying bills in a timely manner and responding to all vendor inquiries regarding finance
Approving purchase requisitions and ensuring that purchase orders are set up.
Keeping track of all payments and expenditures, purchase orders, invoices, and statements
Reconciling credit card statements, including tying back receipts and coding transactions to appropriate general ledger accounts
Setting up vendors in accounting software and reviewing AP ledger monthly
Processing payroll and resolving any issues in a timely manner
Entering new hires and terminations in a payroll system
Assisting the Director of Finance with other tasks as needed

Qualifications

Preferred: Bachelor of Science degree in Accounting, or similar degrees
- 1 – 2 years of experience with journal entries and accounts payable
- 1 – 2 years of experience using accounting software
1 – 2 years of experience using a payroll system
Strong organizational skills and proactive in resolving any issues that may come up.
Attention to detail and sense of ownership.
Strong analytical and problem-solving skills
Demonstrate ability to work independently and work well with people at a wide range of levels.
Experience in the biotech industry is a plus.

Vesigen Therapeutics is an equal-opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

To apply, use the form below.

Don’t see anything that matches your experience? Contact us using the form.

Curing patients with diseases previously impossible to reach

At Vesigen, you’ll join a rapidly growing biotech company engineering the medicines of tomorrow. We are focused on developing therapies that transform patients’ lives.

We value scientific curiosity and collaboration from start to finish. If you share these attributes and you’re ready for the challenge of your career, we’d like to hear from you.

Explore our science

Learn about our breakthrough ARMMs technology.

Learn more